PIAS1 and HECTD2

  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology, unspecified method)

PIAS1

HECTD2

Description protein inhibitor of activated STAT 1 HECT domain E3 ubiquitin protein ligase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Diverticular disease ( 30177863)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Major depressive disorder ( 23377640)
  • Number of twin births ( 30760885)
  • Idiopathic pulmonary fibrosis ( 31710517)
Interacting Genes 107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76 2 interacting genes: PIAS1 UBE2L3
Entrez ID 8554 143279
HPRD ID 16029 13643
Ensembl ID ENSG00000033800 ENSG00000165338
Uniprot IDs O75925 Q1XBU8 B3KV18 B4DIQ2 Q5U5R9 X6R824
PDB IDs 1V66
Enriched GO Terms of Interacting Partners?
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