EAF1 and TRIM62

Data Source:
BioGRID (two hybrid)

		EAF1	TRIM62
Description		ELL associated factor 1	tripartite motif containing 62
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Cytoplasm Cytosol
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Transcription Elongation From RNA Polymerase II Promoter	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Interferon gamma signaling
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		85403	55223
HPRD ID		12209	07697
Ensembl ID		ENSG00000144597	ENSG00000116525
Uniprot IDs		Q96JC9	Q9BVG3
PDB IDs
Enriched GO Terms of Interacting Partners?
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