EAF1 and ARID4B

Data Source:
BioGRID (two hybrid)

		EAF1	ARID4B
Description		ELL associated factor 1	AT-rich interaction domain 4B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Cellular_component Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Molecular_function Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Transcription Elongation From RNA Polymerase II Promoter	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS			Asthma ( 29273806) Monocyte percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494)
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	15 interacting genes: DNAAF6 DYNLT1 EAF1 ETS1 HNRNPA2B1 NHSL2 NTAQ1 PIK3R3 PLEKHF2 PRR23B PTGES3L-AARSD1 RANBP2 SAP130 SIN3A SPANXB1
Entrez ID		85403	51742
HPRD ID		12209	10661
Ensembl ID		ENSG00000144597	ENSG00000054267
Uniprot IDs		Q96JC9	Q4LE39
PDB IDs
Enriched GO Terms of Interacting Partners?
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