TRIM62 and UBXN7

Data Source:
BioGRID (two hybrid)

		TRIM62	UBXN7
Description		tripartite motif containing 62	UBX domain protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Cytosol Nuclear Body VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell	Post-translational Protein Modification
Pathways		Interferon gamma signaling	Neddylation
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)
Interacting Genes		19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25	24 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM168A MAP3K1 MEOX1 MUL1 NEDD8 NFYC PAX5 PAX6 REL SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 VCP ZNRF1
Entrez ID		55223	26043
HPRD ID		07697	19396
Ensembl ID		ENSG00000116525	ENSG00000163960
Uniprot IDs		Q9BVG3	O94888
PDB IDs			1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?
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