COPS3 and FLAD1

Data Source:
BioGRID (two hybrid)

		COPS3	FLAD1
Description		COP9 signalosome subunit 3	flavin adenine dinucleotide synthetase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Mitochondrial Matrix Cytosol Plasma Membrane
	Molecular Function	Protein Binding	FMN Adenylyltransferase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification	FAD Biosynthetic Process Riboflavin Metabolic Process
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53	20 interacting genes: ANXA7 APTX CDKN1A CLVS2 COPS3 CRABP2 DNM2 GEMIN4 GRB7 L3MBTL3 NIF3L1 NUDT21 PRTFDC1 RCC1 REL SDCBP SMN1 TCF4 TK1 TRIM23
Entrez ID		8533	80308
HPRD ID		07262	17887
Ensembl ID		ENSG00000141030	ENSG00000160688
Uniprot IDs		B4DN01 Q9UNS2	Q8NFF5
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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