COPS3 and PRXL2B

Data Source:
BioGRID (two hybrid)

		COPS3	PRXL2B
Description		COP9 signalosome subunit 3	peroxiredoxin like 2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Cytoplasm Endoplasmic Reticulum Cytosol Myelin Sheath Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Antioxidant Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Prostaglandin-F Synthase Activity
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification	Prostaglandin Biosynthetic Process Cellular Oxidant Detoxification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53	4 interacting genes: COPS3 PDPK1 TCP11L1 TNFSF11
Entrez ID		8533	127281
HPRD ID		07262	14513
Ensembl ID		ENSG00000141030	ENSG00000157870
Uniprot IDs		B4DN01 Q9UNS2	A0A0A0MRV4 A0A0A0MT35 A0A2P0CTB1 A0A2P0CU24 Q8TBF2
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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