PPFIA1 and DYNC1I2

Data Source:
BioGRID (two hybrid)

		PPFIA1	DYNC1I2
Description		PTPRF interacting protein alpha 1	dynein cytoplasmic 1 intermediate chain 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Presynaptic Active Zone	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle
	Molecular Function	Protein Binding	Microtubule Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Neurotransmitter Secretion Glutamate Secretion Synapse Organization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Localization To Plasma Membrane	G2/M Transition Of Mitotic Cell Cycle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Regulation Of G2/M Transition Of Mitotic Cell Cycle Transport Along Microtubule Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Ciliary Basal Body-plasma Membrane Docking
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		31 interacting genes: AGTPBP1 CAGE1 CAST CCNH CDK18 CEP70 DNAJC5 DTNB DYNC1I2 ELOA ERC1 ERC2 FAM161A GAS8 GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5A PPP2R5D PTPRC PTPRD PTPRF PTPRS TNNT1 TXLNA YWHAG	8 interacting genes: CCDC136 DCTN1 DYNLRB1 DYNLT1 DYNLT3 NECAB2 PNN PPFIA1
Entrez ID		8500	1781
HPRD ID		11451	04512
Ensembl ID		ENSG00000131626	ENSG00000077380
Uniprot IDs		B3KVS8 Q13136	A0A140VKE9 B4DPZ3 Q13409
PDB IDs		1N7F	5JPW 6F1T 6F1U 6F1Z 6F38 6F3A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?