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LINC00839 and CDC16
Data Source:
BioGRID
(unspecified method)
LINC00839
CDC16
Description
long intergenic non-protein coding RNA 839
cell division cycle 16
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Anaphase-promoting Complex
Cytoplasm
Centrosome
Cytosol
Mitotic Spindle
Molecular Function
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Protein Ubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Protein K11-linked Ubiquitination
Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Monocyte percentage of white cells (
32888494
)
Prudent dietary pattern (
28644415
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
30578418
)
Interacting Genes
82 interacting genes:
ADAMTS15
AKAP13
ALDH16A1
APOL3
BFSP1
CALM1
CC2D1B
CCDC168
CCDC93
CDC16
CEP192
CEP295NL
CHPF
CIZ1
CLGN
CLPTM1
COPB1
DNAH10
DPEP3
EFL1
EID2
EMX1
FAAP100
FAM13B
FBXL5
HAPLN4
IQCN
IRX4
JAKMIP2
KLK14
KRT1
KRT6B
L1CAM
MEX3A
MEX3B
MEX3C
MEX3D
MICAL2
MYO7A
NDUFA2
NOC4L
NOTCH3
NVL
OS9
P4HB
PABPN1
PALM3
PARP6
PHACTR1
PKD1L2
PLOD3
PNPLA3
POMT2
PRSS1
PRSS3
PTBP1
PTEN
PTPRA
QSOX2
RAPGEF6
RIF1
RPLP2
RPTOR
RYR2
SEMA4D
SEPTIN12
SEPTIN9
SERHL2
SLC7A14
SOWAHB
SREBF2
SYNE1
SYNE3
TAS1R3
TCF24
TMC4
TRO
UBE2S
VANGL1
YAP1
YIPF1
ZFPL1
24 interacting genes:
ANAPC10
ANAPC11
ANAPC7
BUB1B
C11orf49
CDC20
CDC23
CDC26
CDC27
DAB2
DNAJA1
FBXO5
FTH1
HINT1
LINC00839
MAD2L1
MAPK9
MTNR1B
PPP5C
SKIL
SMAD2
SMAD3
UBE2S
XRCC5
Entrez ID
84856
8881
HPRD ID
17516
04587
Ensembl ID
ENSG00000185904
ENSG00000130177
Uniprot IDs
A0A024RDZ2
A0A3B3ISD2
B2RCW0
Q13042
PDB IDs
3HYM
4UI9
5A31
5G04
5G05
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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