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LINC00839 and PRSS1
Data Source:
BioGRID
(unspecified method)
LINC00839
PRSS1
Description
long intergenic non-protein coding RNA 839
serine protease 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Collagen-containing Extracellular Matrix
Blood Microparticle
Molecular Function
Serine-type Endopeptidase Activity
Metal Ion Binding
Biological Process
Proteolysis
Digestion
Cobalamin Metabolic Process
Extracellular Matrix Disassembly
Pathways
Activation of Matrix Metalloproteinases
Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs
2H-Benzimidazol-2-amine
Bis(5-Amidino-Benzimidazolyl)Methane
2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester
CRA_17693
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester
Hemi-Babim
CRA_10991
Monoisopropylphosphorylserine
[4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone
Bis(5-Amidino-2-Benzimidazolyl)Methanone
2-(2-Hydroxy-5-Methoxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine
5-Amidino-Benzimidazole
Amylamine
CRA_16847
Bis-Benzamidine
CRA_17312
Zk-806450
[4-({[5-Benzyloxy-1-(3-Carbamimidoyl-Benzyl)-1h-Indole-2-Carbonyl]-Amino}-Methyl)-Phenyl]-Trimethyl-Ammonium
2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine
CRA-9334
4-{[1-Methyl-5-(2-Methyl-Benzoimidazol-1-Ylmethyl)-1h-Benzoimidazol-2-Ylmethyl]-Amino}-Benzamidine
CRA_10762
Aminomethylcyclohexane
2-(2-Hydroxy-Phenyl)-1h-Indole-5-Carboxamidine
Benzylamine
CRA_10655
(1R,2S)-2-Phenylcyclopropanaminium
RPR131247
RWJ-56423
CRA_1802
CRA_10972
CRA_1801
[N-[N-(4-Methoxy-2,3,6-trimethylphenylsulfonyl)-L-aspartyl]-D-(4-amidino-phenylalanyl)]-piperidine
Benzamidine
4-Iodobenzo[B]Thiophene-2-Carboxamidine
CRA_8696
CRA_10433
Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone
4-Fluorobenzylamine
RWJ-51084
1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea
ZK-806711
3,5-Diiodotyrosine
(2S,3R)-2-[[4-(Tert-butylcarbamoyl)piperazine-1-carbonyl]amino]-6-(diaminomethylideneamino)-3-formylhexanoic acid
bis(5-amidino-benzimidazolyl)methanone zinc
CRA_11092
CRA_9785
Diminazene
CRA_1144
6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
Thieno[2,3-B]Pyridine-2-Carboxamidine
Phosphorylisopropane
Zinc;[amino-[2-[[5-[amino(azaniumylidene)methyl]benzimidazol-1-id-2-yl]methyl]benzimidazol-1-id-5-yl]methylidene]azanium
[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine
CRA_9076
N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid
CRA_23653
Cyclotheonamide A
Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate
4-Phenylbutylamine
Phenethylamine
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
Aeruginosin 98-B
3-Phenylpropylamine
RPR128515
ZK-805623
Imino[2-(2-oxo-1,2-dihydro-3-pyridinyl)-1H-benzimidazol-5-yl]methanaminium
Benzo[B]Thiophene-2-Carboxamidine
CRA_10656
CRA_9678
4-PIPERIDIN-4-YLBUTANAL
2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol
2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL
2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL
1,4:3,6-Dianhydro-2-O-(3-carbamimidoylphenyl)-5-O-(4-carbamimidoylphenyl)-D-glucitol
Aprotinin
diethyl [(1R)-1,5-diaminopentyl]boronate
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide
N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
6-fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine
N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE
2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide
(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide
3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-5-METHOXY-1,1'-BIPHENYL-2-OLATE
4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE
5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid
+/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE
2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
2-Naphthalenesulfonic acid
1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID
[N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE
Nafamostat
Camostat
Diseases
Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Cancer (
29299148
)
Meconium ileus in cystic fibrosis (
30807572
)
Methadone dose in opioid dependence (
28115739
)
Pancreatitis (
23143602
)
Interacting Genes
82 interacting genes:
ADAMTS15
AKAP13
ALDH16A1
APOL3
BFSP1
CALM1
CC2D1B
CCDC168
CCDC93
CDC16
CEP192
CEP295NL
CHPF
CIZ1
CLGN
CLPTM1
COPB1
DNAH10
DPEP3
EFL1
EID2
EMX1
FAAP100
FAM13B
FBXL5
HAPLN4
IQCN
IRX4
JAKMIP2
KLK14
KRT1
KRT6B
L1CAM
MEX3A
MEX3B
MEX3C
MEX3D
MICAL2
MYO7A
NDUFA2
NOC4L
NOTCH3
NVL
OS9
P4HB
PABPN1
PALM3
PARP6
PHACTR1
PKD1L2
PLOD3
PNPLA3
POMT2
PRSS1
PRSS3
PTBP1
PTEN
PTPRA
QSOX2
RAPGEF6
RIF1
RPLP2
RPTOR
RYR2
SEMA4D
SEPTIN12
SEPTIN9
SERHL2
SLC7A14
SOWAHB
SREBF2
SYNE1
SYNE3
TAS1R3
TCF24
TMC4
TRO
UBE2S
VANGL1
YAP1
YIPF1
ZFPL1
9 interacting genes:
DEFA5
LINC00839
PTPN4
SERPINA1
SERPINB13
SERPINB8
SERPINF2
SPINK5
TST
Entrez ID
84856
5644
HPRD ID
17516
02039
Ensembl ID
ENSG00000185904
ENSG00000204983
Uniprot IDs
P07477
PDB IDs
1FXY
1TRN
2RA3
4WWY
4WXV
Enriched GO Terms of Interacting Partners
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