PSRC1 and ASB7

Data Source:
BioGRID (enzymatic study)

		PSRC1	ASB7
Description		proline and serine rich coiled-coil 1	ankyrin repeat and SOCS box containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Spindle Cytosol Spindle Microtubule Microtubule Cytoskeleton Midbody	Cytosol
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding
	Biological Process	Microtubule Bundle Formation Mitotic Metaphase Plate Congression Negative Regulation Of Cell Growth Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Cell Division Regulation Of Mitotic Spindle Organization	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 27899403) Blood protein levels ( 28240269) Cholesterol ( 31902109) Cholesterol, total ( 20686565) Coronary artery disease ( 32469254 29212778) Coronary heart disease ( 17634449 21378988) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) LDL cholesterol ( 18262040 18179892 18193043 18193044 19060906 19060910 21347282 20686565) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Lipid metabolism phenotypes ( 19936222) Lipoprotein-associated phospholipase A2 activity and mass ( 20442857) Low density lipoprotein cholesterol levels ( 30718733) Medication use (salicylic acid and derivatives) ( 31015401) Metabolite levels ( 21909109) Myocardial infarction (early onset) ( 19198609) Parental lifespan ( 30642433) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Progranulin levels ( 21087763 29186428) Response to statin therapy ( 20339536) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)	Anti-drug antibodies in autoimmune disease (time to event) ( 33125391) Chin dimples ( 27182965) Chronotype ( 30696823) Lower body strength ( 27325353) Morning person ( 30696823) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 28073927) Response to taxane treatment (placlitaxel) ( 23006423) Vertical cup-disc ratio ( 31798171 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		4 interacting genes: APP ASB7 MAPRE3 SRGN	6 interacting genes: ATF4 CCDC136 HIF1AN HMBOX1 PSRC1 ZFAND2B
Entrez ID		84722	140460
HPRD ID		13127	10674
Ensembl ID		ENSG00000134222	ENSG00000183475
Uniprot IDs		A0A024R099 A8K0M8 Q6PGN9	A0A024RC94 A0A024RCD9 Q9H672
PDB IDs
Enriched GO Terms of Interacting Partners?
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