ASB7 and ZFAND2B

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ASB7	ZFAND2B
Description		ankyrin repeat and SOCS box containing 7	zinc finger AN1-type containing 2B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Proteasome Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Protein Targeting To ER
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Anti-drug antibodies in autoimmune disease (time to event) ( 33125391) Chin dimples ( 27182965) Chronotype ( 30696823) Lower body strength ( 27325353) Morning person ( 30696823) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 28073927) Response to taxane treatment (placlitaxel) ( 23006423) Vertical cup-disc ratio ( 31798171 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: ATF4 CCDC136 HIF1AN HMBOX1 PSRC1 ZFAND2B	7 interacting genes: ASB7 DAZAP2 RHOU TARDBP UBC UBQLN1 UBQLN2
Entrez ID		140460	130617
HPRD ID		10674	11234
Ensembl ID		ENSG00000183475	ENSG00000158552
Uniprot IDs		A0A024RC94 A0A024RCD9 Q9H672	A0A087X0D9 Q8WV99
PDB IDs			1X4V
Enriched GO Terms of Interacting Partners?
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