ATG7 and ATG10

Data Source:
HPRD (two hybrid)

		ATG7	ATG10
Description		autophagy related 7	autophagy related 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Axon Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Cytosol
	Molecular Function	Protein Binding Transcription Factor Binding Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity	Protein Binding Atg12 Transferase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation C-terminal Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Aging Cellular Response To Starvation Response To Glucose Protein Transport Macroautophagy Protein Phosphopantetheinylation Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Piecemeal Microautophagy Of The Nucleus Suppression By Virus Of Host Autophagy Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Neutrophil Degranulation Late Nucleophagy Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Chaperone-mediated Autophagy Cellular Response To Morphine Cellular Response To Hyperoxia Positive Regulation By Symbiont Of Host Autophagy Negative Regulation Of Mitochondrial DNA Replication Response To Fluoride Negative Regulation Of Oxidative Stress-induced Neuron Death	Protein Lipidation Autophagy ER Overload Response Protein Transport Macroautophagy Protein Phosphopantetheinylation Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation
Pathways		Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF fusions Antigen processing: Ubiquitination & Proteasome degradation	Macroautophagy Macroautophagy
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Body size at age 10 ( 32376654) Circulating chemerin levels ( 25521368) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 28869591) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) Relative hand skill in reading disability ( 24068947) Small vessel stroke ( 29123153) Systolic blood pressure ( 27618447 27618452 30578418)	Adventurousness ( 30643258) Airway imaging phenotypes ( 26030696) Breast cancer ( 25751625 29059683) Carotid intima media thickness (mean) ( 31801372) General risk tolerance (MTAG) ( 30643258)
Interacting Genes		10 interacting genes: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B	4 interacting genes: ATG12 ATG5 ATG7 IRGM
Entrez ID		10533	83734
HPRD ID		12293	16497
Ensembl ID		ENSG00000197548	ENSG00000152348
Uniprot IDs		B3KQM6 O95352	Q9H0Y0
PDB IDs
Enriched GO Terms of Interacting Partners?
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