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ZMAT1 and ALAS1
Data Source:
BioGRID
(two hybrid, two hybrid)
ZMAT1
ALAS1
Description
zinc finger matrin-type 1
5'-aminolevulinate synthase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Molecular Function
DNA Binding
Zinc Ion Binding
5-aminolevulinate Synthase Activity
Protein Binding
Pyridoxal Phosphate Binding
Identical Protein Binding
Biological Process
Response To Hypoxia
Protoporphyrinogen IX Biosynthetic Process
Heme Biosynthetic Process
Mitochondrion Organization
Regulation Of Lipid Metabolic Process
Hemoglobin Biosynthetic Process
Erythrocyte Development
Pathways
Heme biosynthesis
PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Drugs
Pyridoxal phosphate
Pyridoxal phosphate
Glycine
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
21926972
)
Parkinson's disease (
28892059
)
Schizophrenia (
23974872
)
Interacting Genes
23 interacting genes:
ABL2
ALAS1
BLK
BLZF1
C1orf109
CDC23
DUSP21
EXOSC5
GOLGA2
GORASP2
GRB2
HOXA1
LZTS2
MYO15B
OIP5
PIK3R3
QRICH1
RFC5
RUNX1T1
SAXO1
SCNM1
STK16
ZNF124
54 interacting genes:
BCL7A
C2orf42
C8orf33
CAP2
CCHCR1
CDC73
CDK5
CDKN1A
CERK
COBL
DUSP19
EP400
FBXL8
GNL3L
GRXCR1
HSBP1L1
JRK
KIF9
KLHL35
LONRF1
LRRC45
MTFR2
MTSS2
NUDT3
OXTR
PIBF1
PIK3CB
PLAU
POLDIP2
PPL
RAP1B
RNF168
RTL8B
SH2D4A
SNRPB2
SNX20
STAMBP
SUMO2
TCEA2
TEKT4
TK1
TMSB10
TMSB4X
TMSB4XP1
TMSB4XP2
TMSB4XP6
TTC23
USP20
UTP14C
WIPF1
ZFYVE26
ZMAT1
ZNF175
ZNF564
Entrez ID
84460
211
HPRD ID
10029
00505
Ensembl ID
ENSG00000166432
ENSG00000023330
Uniprot IDs
A0A494C0A7
A7MD47
Q5H9K5
B4DVA0
P13196
Q5JAM2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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