POLR1B and LZTR1

Data Source:
BioGRID (two hybrid)

		POLR1B	LZTR1
Description		RNA polymerase I subunit B	leucine zipper like transcription regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Cytosol	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ribonucleoside Binding Metal Ion Binding	Protein Binding Small GTPase Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Embryo Implantation RRNA Transcription Nucleologenesis Positive Regulation Of Gene Expression, Epigenetic	Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207	55 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 GABARAPL2 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RIT1 RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		84172	8216
HPRD ID		06852	08992
Ensembl ID		ENSG00000125630	ENSG00000099949
Uniprot IDs		B7Z1W6 Q9H9Y6	A0A384NL67 Q8N653
PDB IDs
Enriched GO Terms of Interacting Partners?
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