GLE1 and UXT

Data Source:
BioGRID (two hybrid)

		GLE1	UXT
Description		GLE1 RNA export mediator	ubiquitously expressed prefoldin like chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	MRNA Export From Nucleus Regulation Of Translational Initiation Regulation Of Translational Termination Poly(A)+ MRNA Export From Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript	Transcriptional Regulation by E2F6
Drugs
Diseases		Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)
GWAS		Axial length ( 24144296) Body mass index ( 26426971)
Interacting Genes		4 interacting genes: KRT10 NUP155 NUP42 UXT	29 interacting genes: APP AR CECR2 DYNLT1 FBXO7 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL
Entrez ID		2733	8409
HPRD ID		04536	02209
Ensembl ID		ENSG00000119392	ENSG00000126756
Uniprot IDs		B3KMG0 Q53GS7	Q9UBK9
PDB IDs		6B4F 6B4I 6B4J
Enriched GO Terms of Interacting Partners?
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