CAPZB and MTPN

Data Source:
HPRD (in vivo)

		CAPZB	MTPN
Description		capping actin protein of muscle Z-line subunit beta	myotrophin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Extracellular Exosome WASH Complex	Nucleus Cytoplasm Cytosol F-actin Capping Protein Complex Axon Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding	Sequence-specific DNA Binding
	Biological Process	Cell Morphogenesis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly	Regulation Of Translation Catecholamine Metabolic Process Regulation Of Cell Size Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Striated Muscle Tissue Development Cerebellar Granule Cell Differentiation Neuron Differentiation Positive Regulation Of Cell Growth Skeletal Muscle Tissue Regeneration Positive Regulation Of NF-kappaB Transcription Factor Activity Striated Muscle Cell Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Mechanical Stimulus Regulation Of Barbed-end Actin Filament Capping
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)	Alcoholic chronic pancreatitis ( 28754779) Mean platelet volume ( 32888494) Platelet count ( 27863252) Platelet distribution width ( 32888494 27863252) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		9 interacting genes: BCCIP CDC42 HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL	5 interacting genes: CAPZB MAPK1 NFKB1 REL RELA
Entrez ID		832	136319
HPRD ID		11872	07574
Ensembl ID		ENSG00000077549	ENSG00000105887
Uniprot IDs		A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0	P58546 Q69YG1
PDB IDs			3AAA
Enriched GO Terms of Interacting Partners?
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