CAPZB and MRPL20

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPZB	MRPL20
Description		capping actin protein of muscle Z-line subunit beta	mitochondrial ribosomal protein L20
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Extracellular Exosome WASH Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Cell Morphogenesis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly	Ribosomal Large Subunit Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)	Diastolic blood pressure ( 30578418) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		9 interacting genes: BCCIP CDC42 HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL	11 interacting genes: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ERCC6 ITSN1 OXA1L TP53BP2 USP13
Entrez ID		832	55052
HPRD ID		11872	14746
Ensembl ID		ENSG00000077549	ENSG00000242485
Uniprot IDs		A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0	Q9BYC9
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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