SMC1A and ATM

  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, enzymatic study)
  • HPRD (in vitro, in vivo)

SMC1A

ATM

Description structural maintenance of chromosomes 1A ATM serine/threonine kinase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 20 interacting genes: AMOT ATM BLM BRCA1 ESR1 FGF14 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3 SUMO2 98 interacting genes: AATF ABL1 ACTL6B AP1B1 AP2B1 AP3B1 AP3B2 ATR BCAS3 BCL10 BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 COPS5 CREB1 CRX CSNK1D CXXC5 DAXX DCAF1 DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 ERRFI1 ESRRG EXO1 FANCD2 FECH FOXO3 H2AX HIF1A HSPA8 IL24 KAT5 KAT8 LIG4 MAP1S MCM2 MCPH1 MDC1 MDM2 MDM4 MRE11 MT-ND4 MTA3 NBN NR4A1 NREP NSD3 OSGIN1 PARP1 PEX5 POLR2A PPP2R5C PRKDC PTCH1 RAD17 RAD51 RAD9A RANBP9 RASSF1 RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TFF1 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 TRIM29 UCHL3 WRN XPA XRCC5 ZEB1 ZNF821
Entrez ID 8243 472
HPRD ID 02077 06347
Ensembl ID ENSG00000072501 ENSG00000149311
Uniprot IDs A0A384MR33 G8JLG1 Q14683 Q68EN4 A0A024R3C7 Q13315
PDB IDs 6WG3 6WG4 6WG6 6WGE 5NP0 5NP1 6HKA 6K9K 6K9L
Enriched GO Terms of Interacting Partners?
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