SMC1A

Description		structural maintenance of chromosomes 1A
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Mitotic Spindle Pole
	Molecular Function	DNA Binding Chromatin Binding RNA Binding Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Sister Chromatid Segregation DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Response To Radiation Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Response To DNA Damage Checkpoint Signaling Mitotic Spindle Assembly
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases		Cornelia de Lange syndrome (CdLS)
GWAS		Bipolar disorder ( 31043756) Mean corpuscular volume ( 32888494)
Novel Interacting Genes		1 novel interacting genes: ALK
Interacting Genes		20 interacting genes: AMOT ATM BLM BRCA1 ESR1 FGF14 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3 SUMO2
Entrez ID		8243
HPRD ID		02077
Ensembl ID		ENSG00000072501
Uniprot IDs		A0A384MR33 G8JLG1 Q14683 Q68EN4
PDB IDs		6WG3 6WG4 6WG6 6WGE
Enriched GO Terms of Interacting Partners?
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