ZRSR2 and SRSF2

Data Source:
HPRD (two hybrid, in vitro)

		ZRSR2	SRSF2
Description		zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2	serine and arginine rich splicing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex	Nucleus Nucleoplasm Cytoplasm Cytosol PML Body Nuclear Speck
	Molecular Function	Protein Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding	Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of Transcription, DNA-templated
Pathways		mRNA Splicing - Minor Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: APP CCNL1 CLK2 DVL3 KHDC4 LUC7L2 REP15 SDCBP2 SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2 ZRSR2P1	34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		8233	6427
HPRD ID		02068	02888
Ensembl ID		ENSG00000169249	ENSG00000161547
Uniprot IDs		Q15696	A0A024R8U5 Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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