SRSF2 and CCNL2

Data Source:
HPRD (in vivo)

		SRSF2	CCNL2
Description		serine and arginine rich splicing factor 2	cyclin L2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol PML Body Nuclear Speck	Nucleus Nucleoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of Transcription, DNA-templated	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2	15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B
Entrez ID		6427	81669
HPRD ID		02888	10815
Ensembl ID		ENSG00000161547	ENSG00000221978
Uniprot IDs		A0A024R8U5 Q01130 Q53FN0	Q96S94
PDB IDs		2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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