GAN and MAP1B

Data Source:
HPRD (in vitro, in vivo)

		GAN	MAP1B
Description		gigaxonin	microtubule associated protein 1B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Photoreceptor Outer Segment Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Axon Dendrite Growth Cone Somatodendritic Compartment Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber
	Molecular Function	Molecular_function Protein Binding	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Protein-containing Complex Binding
	Biological Process	Cytoskeleton Organization Protein Ubiquitination Post-translational Protein Modification	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Axonogenesis Synapse Assembly Response To Mechanical Stimulus Response To Carbohydrate Cellular Process Response To Inorganic Substance Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age-related cataracts ( 25352737) Health literacy ( 31250787) Post bronchodilator FEV1 ( 26634245) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ATG16L1 MAP1B TBCB UBA1	29 interacting genes: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D ERBB3 FOS GABRR1 GABRR2 GAN GSK3B HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2
Entrez ID		8139	4131
HPRD ID		05647	01139
Ensembl ID		ENSG00000261609	ENSG00000131711
Uniprot IDs		A0A0S2Z4W2 B3KTC3 Q9H2C0	A2BDK6 P46821 Q6PJD3 Q86X89
PDB IDs		2PPI 3HVE
Enriched GO Terms of Interacting Partners?
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