MAP1B and HTR6

Data Source:
BioGRID (pull down, affinity chromatography technology)

		MAP1B	HTR6
Description		microtubule associated protein 1B	5-hydroxytryptamine receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Axon Dendrite Growth Cone Somatodendritic Compartment Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Protein-containing Complex Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Axonogenesis Synapse Assembly Response To Mechanical Stimulus Response To Carbohydrate Cellular Process Response To Inorganic Substance Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241) Refractive error ( 32231278)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		29 interacting genes: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D ERBB3 FOS GABRR1 GABRR2 GAN GSK3B HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2	31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		4131	3362
HPRD ID		01139	03066
Ensembl ID		ENSG00000131711	ENSG00000158748
Uniprot IDs		A2BDK6 P46821 Q6PJD3 Q86X89	P50406
PDB IDs
Enriched GO Terms of Interacting Partners?
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