ACTN4 and NOS3

  • Data Source:
  • BioGRID (two hybrid)

ACTN4

NOS3

Description actinin alpha 4 nitric oxide synthase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Heart rate ( 23583979)
  • Immature fraction of reticulocytes ( 32888494)
  • Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
  • Mean platelet volume ( 32888494)
  • Retinal venular tortuosity ( 31597446)
  • Waist circumference ( 28552196)
  • Coronary artery disease ( 29212778 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Diastolic blood pressure ( 27841878 28739976 27618448)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Estimated glomerular filtration rate ( 31451708)
  • Eyebrow thickness ( 26926045)
  • Hypertension ( 27618448)
  • Mean arterial pressure ( 27618448)
  • Mean platelet volume ( 32888494)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Periventricular white matter hyperintensities ( 32517579)
  • Platelet distribution width ( 32888494)
  • Stroke ( 30383316)
  • Systolic blood pressure ( 27841878 27618448 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 55 interacting genes: ACTC1 ACTN3 ADORA2A ATP6V1B1 ATXN7 BMP7 C14orf119 CAMK2A CAMK2B CAMK2G CDKN2A COIL COL17A1 DDIAS ESR1 GSN HDAC7 HSPB1 INO80 ITGB1 KPNA2 LCMT2 LNX1 LRRC7 MAGI1 MAPK7 MEF2A MEOX2 MICALL2 MYOZ1 MYOZ2 NEB NOS2 NOS3 PDLIM1 POT1 PTGER4 PTPN11 PTPN6 RARA RPS27 SACS SERPINE1 SLC2A4 SLC9A3R2 SORBS2 STAT1 TJP1 TRIM23 TRIM3 TTN TXN UCHL5 USP6NL VDR 47 interacting genes: A2M ACTN2 ACTN4 AGTR1 AKT1 APOE APP BDKRB2 BDNF CALM1 CAV1 CDC37 CEP55 EDNRB EFEMP1 EFEMP2 ELAVL1 ELAVL3 EXOC6 EXOSC1 FIS1 GCDH GOLGA2 H3-3A HSP90AA1 HTRA1 IKZF3 IMMT KANK2 MAGEA11 MAST1 MPRIP NMT1 NOSIP NOSTRIN PAXIP1 PI4K2A PPP2R5A PSEN1 PSEN2 RNF31 RNF32 SP1 ST13 TECR TXNDC11 UMPS
Entrez ID 81 4846
HPRD ID 05222 01224
Ensembl ID ENSG00000130402 ENSG00000164867
Uniprot IDs A0A0S2Z3G9 O43707 A0S0A6 P29474
PDB IDs 1WLX 1YDI 2R0O 6O31 6OA6 1M9J 1M9K 1M9M 1M9Q 1M9R 1NIW 2LL7 2MG5 2N8J 3EAH 3NOS 4D1O 4D1P 5UO8 5UO9 5UOA 5UOB 5UOC 5VVB 5VVC 5VVD 5XOF 6AV6 6AV7 6CIE 6CIF 6NH1 6NH2 6NH3 6NH4 6NH5 6NH6 6NH7 6NH8 6NHF 6POU 6POV 6POW 6POX 6POY 6POZ 6PP0 6PP1 6PP2 6PP3 6PP4
Enriched GO Terms of Interacting Partners?
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