PRR3 and APOBEC3C

Data Source:
BioGRID (two hybrid)

		PRR3	APOBEC3C
Description		proline rich 3	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Image		No pdb structure
GO Annotations	Cellular Component		P-body Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process		Cytidine Deamination Negative Regulation Of Transposition Viral Process Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Itch intensity from mosquito bite ( 28199695) Neuroticism ( 29255261)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		21 interacting genes: APOBEC3C ASF1A BCL2L2-PABPN1 CCDC57 CLP1 HNRNPK KHDRBS2 KHDRBS3 KLF1 KRTAP6-2 KRTAP6-3 MYPOP NXF1 PSMA3 RAMAC RBM3 RBMX RBMY1A1 RBMY1F RBMY1J TLE5	17 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		80742	27350
HPRD ID		17915	09671
Ensembl ID		ENSG00000204576	ENSG00000244509
Uniprot IDs		B3KQA4 P79522 Q96QB9	Q9NRW3
PDB IDs			3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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