APOBEC3C and ZNF48

Data Source:
BioGRID (two hybrid)

		APOBEC3C	ZNF48
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 3C	zinc finger protein 48
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm	Nucleus
	Molecular Function	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cytidine Deamination Negative Regulation Of Transposition Viral Process Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		17 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581	18 interacting genes: APOBEC3C BYSL CEP55 EIF3E FNDC11 GOLGA2 GOLGA6L9 HOOK2 MORF4L2 MTUS2 OSBPL3 PRPF31 SF3B4 TACC1 TLE5 TRIM41 ZNF774 ZNF792
Entrez ID		27350	197407
HPRD ID		09671	15836
Ensembl ID		ENSG00000244509	ENSG00000180035
Uniprot IDs		Q9NRW3	A0A087WVT1 Q96MX3
PDB IDs		3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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