Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
APOBEC3C and TRIB3
Data Source:
BioGRID
(two hybrid)
APOBEC3C
TRIB3
Description
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
tribbles pseudokinase 3
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Molecular Function
RNA Binding
Cytidine Deaminase Activity
Protein Binding
Zinc Ion Binding
Deoxycytidine Deaminase Activity
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Protein Kinase Binding
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Biological Process
Cytidine Deamination
Negative Regulation Of Transposition
Viral Process
Cytidine To Uridine Editing
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Defense Response To Virus
DNA Cytosine Deamination
DNA Demethylation
Negative Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Regulation Of Autophagy
Regulation Of Glucose Transmembrane Transport
Regulation Of Lipid Metabolic Process
Positive Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
mRNA Editing: C to U Conversion
Formation of the Editosome
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Response to methotrexate in juvenile idiopathic arthritis (
24709693
)
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Interacting Genes
17 interacting genes:
CHTOP
FBXO7
HHEX
HNRNPK
PRR3
RBMX
RBMY1A1
RBMY1F
RBMY1J
SHBG
SRPK2
TRAF3
TRIB3
ZNF250
ZNF408
ZNF48
ZNF581
99 interacting genes:
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MISP
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PPP1R32
PRKAB2
PRMT5
PRR19
PSMA3
RARA
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SQSTM1
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
Entrez ID
27350
57761
HPRD ID
09671
09836
Ensembl ID
ENSG00000244509
ENSG00000101255
Uniprot IDs
Q9NRW3
B4DMM9
J3KR25
Q96RU7
PDB IDs
3VM8
3VOW
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?