WDR61 and TCEA1

Data Source:
BioGRID (pull down)

		WDR61	TCEA1
Description		WD repeat domain 61	transcription elongation factor A1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cdc73/Paf1 Complex Transcriptionally Active Chromatin Ski Complex	Nucleoplasm Transcription Factor TFIID Complex Nucleolus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Wnt Signaling Pathway Protein Ubiquitination Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity
Pathways		Formation of RNA Pol II elongation complex mRNA decay by 3' to 5' exoribonuclease RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Reticulocyte count ( 32888494)	Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		11 interacting genes: ACVR1 BARD1 ERRFI1 EZH2 MCPH1 MSRB3 PRNP SMURF1 TCEA1 TGFBR1 YWHAQ	18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		80349	6917
HPRD ID		15236	03252
Ensembl ID		ENSG00000140395	ENSG00000187735
Uniprot IDs		H0YL19 Q9GZS3	A0A384MTX4 B7Z4W0 P23193
PDB IDs		3OW8 6GMH 6TED	1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L
Enriched GO Terms of Interacting Partners?
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