TCEA1 and WDR61

Data Source:
BioGRID (pull down)

		TCEA1	WDR61
Description		transcription elongation factor A1	WD repeat domain 61
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol Cdc73/Paf1 Complex Transcriptionally Active Chromatin Ski Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Wnt Signaling Pathway Protein Ubiquitination Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex mRNA decay by 3' to 5' exoribonuclease RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio ( 26631737)	Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Reticulocyte count ( 32888494)
Interacting Genes		18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61	11 interacting genes: ACVR1 BARD1 ERRFI1 EZH2 MCPH1 MSRB3 PRNP SMURF1 TCEA1 TGFBR1 YWHAQ
Entrez ID		6917	80349
HPRD ID		03252	15236
Ensembl ID		ENSG00000187735	ENSG00000140395
Uniprot IDs		A0A384MTX4 B7Z4W0 P23193	H0YL19 Q9GZS3
PDB IDs		1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L	3OW8 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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