TCEA1 and REXO1

Data Source:
HPRD (in vitro)

		TCEA1	REXO1
Description		transcription elongation factor A1	RNA exonuclease 1 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Nucleolus	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity	Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio ( 26631737)	Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61	4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1
Entrez ID		6917	57455
HPRD ID		03252	15478
Ensembl ID		ENSG00000187735	ENSG00000079313
Uniprot IDs		A0A384MTX4 B7Z4W0 P23193	Q8N1G1
PDB IDs		1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L
Enriched GO Terms of Interacting Partners?
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