MED28 and RAP1GDS1

Data Source:
BioGRID (affinity chromatography technology)

		MED28	RAP1GDS1
Description		mediator complex subunit 28	Rap1 GTPase-GDP dissociation stimulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Membrane Mediator Complex Cortical Actin Cytoskeleton	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Stem Cell Population Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		17 interacting genes: CBY2 FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 MIIP NF2 PRMT6 PUF60 SRC SUOX TCP11 USHBP1	23 interacting genes: CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS MBIP NRAS PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451
Entrez ID		80306	5910
HPRD ID		14381	11763
Ensembl ID		ENSG00000118579	ENSG00000138698
Uniprot IDs		Q9H204	B3KNU0 P52306 Q6U7G8
PDB IDs			5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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