TMEM254 and IL3RA

		TMEM254	IL3RA
Description		transmembrane protein 254	interleukin 3 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Binding	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding
	Biological Process		MAPK Cascade Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway
Pathways			Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs			Sargramostim Tagraxofusp
Diseases
GWAS			Schizophrenia ( 17522711)
Interacting Genes		41 interacting genes: AQP6 ARL13B ATP6V0E1 BCL2L13 BIK CD74 CD79A CERS4 CPLX4 EBP ELOVL4 FAM209A FKBP8 FNDC9 GPR152 GPX8 IFNGR2 IL3RA LEUTX LHFPL5 MFF MMGT1 MTIF3 PAGE1 PLP1 REEP4 RETREG3 SAR1A SEC11C SLC16A2 STOM STX1A SYT1 TMED8 TMEM14B TMEM237 TMEM31 TMEM45B TMEM51 TMEM79 TMX2	32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5
Entrez ID		80195	3563
HPRD ID		08501	02392
Ensembl ID		ENSG00000133678	ENSG00000185291
Uniprot IDs		A0A087WZM8 B4DU43 Q8TBM7	P26951
PDB IDs			4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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