IL3RA and SGK2

Data Source:
BioGRID (two hybrid)

		IL3RA	SGK2
Description		interleukin 3 receptor subunit alpha	serum/glucocorticoid regulated kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Nucleoplasm Cytosol
	Molecular Function	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding	Protein Serine/threonine Kinase Activity ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MAPK Cascade Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway	Regulation Of Cell Growth Protein Phosphorylation Response To Oxidative Stress Peptidyl-serine Phosphorylation Positive Regulation Of Transporter Activity Ion Transmembrane Transport Intracellular Signal Transduction Regulation Of Cell Population Proliferation
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling	Stimuli-sensing channels
Drugs		Sargramostim Tagraxofusp
Diseases
GWAS		Schizophrenia ( 17522711)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5	8 interacting genes: APP DAPK1 HIRIP3 IL3RA NEDD4 NEDD4L PDPK1 PMM2
Entrez ID		3563	10110
HPRD ID		02392	06348
Ensembl ID		ENSG00000185291	ENSG00000101049
Uniprot IDs		P26951	Q9HBY8
PDB IDs		4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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