SIKE1 and CENPQ

		SIKE1	CENPQ
Description		suppressor of IKBKE 1	centromere protein Q
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Kinetochore Nucleus Nucleoplasm Cytosol Actin Cytoskeleton
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding	Protein Binding
	Biological Process		CENP-A Containing Nucleosome Assembly Metaphase Plate Congression Positive Regulation Of Protein Localization To Kinetochore
Pathways		TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C	14 interacting genes: AARD ABI2 ABI3 APP ATF2 BRME1 CCDC6 EMILIN1 HDAC7 HOMER1 KDM1A PLK1 SIKE1 SNX2
Entrez ID		80143	55166
HPRD ID		07958	10788
Ensembl ID		ENSG00000052723	ENSG00000031691
Uniprot IDs		Q9BRV8	Q7L2Z9
PDB IDs		6AKK 6AKL 6AKM
Enriched GO Terms of Interacting Partners?
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