CENPQ and SIKE1

		CENPQ	SIKE1
Description		centromere protein Q	suppressor of IKBKE 1
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytosol Actin Cytoskeleton	Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Small GTPase Binding
	Biological Process	CENP-A Containing Nucleosome Assembly Metaphase Plate Congression Positive Regulation Of Protein Localization To Kinetochore
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		14 interacting genes: AARD ABI2 ABI3 APP ATF2 BRME1 CCDC6 EMILIN1 HDAC7 HOMER1 KDM1A PLK1 SIKE1 SNX2	13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C
Entrez ID		55166	80143
HPRD ID		10788	07958
Ensembl ID		ENSG00000031691	ENSG00000052723
Uniprot IDs		Q7L2Z9	Q9BRV8
PDB IDs			6AKK 6AKL 6AKM
Enriched GO Terms of Interacting Partners?
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