CENPQ and BRME1

Data Source:
BioGRID (two hybrid)

		CENPQ	BRME1
Description		centromere protein Q	break repair meiotic recombinase recruitment factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytosol Actin Cytoskeleton	Cellular_component Chromosome
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	CENP-A Containing Nucleosome Assembly Metaphase Plate Congression Positive Regulation Of Protein Localization To Kinetochore	Multicellular Organism Development Spermatogenesis Double-strand Break Repair Involved In Meiotic Recombination
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		14 interacting genes: AARD ABI2 ABI3 APP ATF2 BRME1 CCDC6 EMILIN1 HDAC7 HOMER1 KDM1A PLK1 SIKE1 SNX2	32 interacting genes: ADAMTSL4 AIMP2 APP C19orf25 CENPQ COPS4 CTNNAL1 CYSRT1 EWSR1 FAM9B FBXO25 GPS2 HAUS3 HOMER1 IKBKG KRT31 KRT34 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NBPF19 NOTCH2NLA PSMA6 RABL6 RUNX1T1 STXBP1 TRIM23 TSC22D3 VCL
Entrez ID		55166	79173
HPRD ID		10788	14415
Ensembl ID		ENSG00000031691	ENSG00000132016
Uniprot IDs		Q7L2Z9	Q0VDD7
PDB IDs
Enriched GO Terms of Interacting Partners?
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