PSCA and SLC35A1

Data Source:
BioGRID (two hybrid)

		PSCA	SLC35A1
Description		prostate stem cell antigen	solute carrier family 35 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane
	Molecular Function	Acetylcholine Receptor Binding	CMP-N-acetylneuraminate Transmembrane Transporter Activity UDP-galactose Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity	Carbohydrate Metabolic Process Cellular Protein Modification Process Carbohydrate Transport CMP-N-acetylneuraminate Transmembrane Transport UDP-galactose Transmembrane Transport
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Sialic acid metabolism Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Transport of nucleotide sugars
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)	Bone mineral density (hip) ( 30172743) Obesity-related traits ( 23251661)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	36 interacting genes: AQP6 ARL13B ASGR2 ASZ1 BCL2L13 CD53 CERS4 CPLX4 EBAG9 ERGIC3 F11R F2RL1 FAM209A FNDC9 FXYD3 GPX8 KIR3DL3 LHFPL5 LMNA MCFD2 MGST3 MRPS18B PIK3IP1 PLPP4 PSCA RELL2 SAR1A SDC3 SLC1A1 SLC34A2 SSMEM1 SYT2 TCTA TMEM139 TMPRSS2 TMX2
Entrez ID		8000	10559
HPRD ID		03919	09290
Ensembl ID		ENSG00000167653	ENSG00000164414
Uniprot IDs		D3DWI6 O43653	P78382
PDB IDs
Enriched GO Terms of Interacting Partners?
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