SLC35A1 and ASGR2

Data Source:
BioGRID (two hybrid)

		SLC35A1	ASGR2
Description		solute carrier family 35 member A1	asialoglycoprotein receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	CMP-N-acetylneuraminate Transmembrane Transporter Activity UDP-galactose Transmembrane Transporter Activity Protein Binding Antiporter Activity	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Carbohydrate Metabolic Process Cellular Protein Modification Process Carbohydrate Transport CMP-N-acetylneuraminate Transmembrane Transport UDP-galactose Transmembrane Transport	Endocytosis Cell Surface Receptor Signaling Pathway Viral Process Protein N-linked Glycosylation Via Asparagine Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Sialic acid metabolism Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Transport of nucleotide sugars	Asparagine N-linked glycosylation
Drugs			Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS		Bone mineral density (hip) ( 30172743) Obesity-related traits ( 23251661)	Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Total cholesterol levels ( 30275531)
Interacting Genes		36 interacting genes: AQP6 ARL13B ASGR2 ASZ1 BCL2L13 CD53 CERS4 CPLX4 EBAG9 ERGIC3 F11R F2RL1 FAM209A FNDC9 FXYD3 GPX8 KIR3DL3 LHFPL5 LMNA MCFD2 MGST3 MRPS18B PIK3IP1 PLPP4 PSCA RELL2 SAR1A SDC3 SLC1A1 SLC34A2 SSMEM1 SYT2 TCTA TMEM139 TMPRSS2 TMX2	49 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1
Entrez ID		10559	433
HPRD ID		09290	00152
Ensembl ID		ENSG00000164414	ENSG00000161944
Uniprot IDs		P78382	P07307 Q7Z4G9
PDB IDs
Enriched GO Terms of Interacting Partners?
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