PSCA and TMEM54

Data Source:
BioGRID (two hybrid)

		PSCA	TMEM54
Description		prostate stem cell antigen	transmembrane protein 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome	Cellular_component Integral Component Of Membrane
	Molecular Function	Acetylcholine Receptor Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity	Biological_process
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	24 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B
Entrez ID		8000	113452
HPRD ID		03919	12524
Ensembl ID		ENSG00000167653	ENSG00000121900
Uniprot IDs		D3DWI6 O43653	Q969K7
PDB IDs
Enriched GO Terms of Interacting Partners?
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