SLC35E1 and MCOLN1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC35E1	MCOLN1
Description		solute carrier family 35 member E1	mucolipin TRP cation channel 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Integral Component Of Membrane	Phagocytic Cup Nucleoplasm Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Late Endosome Membrane Cell Projection Intracellular Membrane-bounded Organelle Receptor Complex
	Molecular Function	Protein Binding Antiporter Activity	Cation Channel Activity Iron Ion Transmembrane Transporter Activity Protein Binding Lipid Binding NAADP-sensitive Calcium-release Channel Activity Intracellular Phosphatidylinositol-3,5-bisphosphate-sensitive Cation Channel Activity Ligand-gated Calcium Channel Activity
	Biological Process	Transmembrane Transport	Adaptive Immune Response Cation Transport Calcium-mediated Signaling Transferrin Transport Iron Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Cellular Response To PH Phagosome Maturation Autophagosome Maturation
Pathways			TRP channels Transferrin endocytosis and recycling
Drugs
Diseases			Mucolipidosis IV
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494) Opioid overdose severity score ( 31362332)
Interacting Genes		6 interacting genes: ABCF3 FTHL17 FXYD6 LAMA3 MCOLN1 MPP1	5 interacting genes: APPBP2 GPR35 SEC22A SLC35E1 TRIM27
Entrez ID		79939	57192
HPRD ID		15373	05582
Ensembl ID		ENSG00000127526	ENSG00000090674
Uniprot IDs		A0A024R7G7 Q96K37	Q9GZU1
PDB IDs			5TJA 5TJB 5TJC 5WJ5 5WJ9 6E7P 6E7Y 6E7Z
Enriched GO Terms of Interacting Partners?
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