MCOLN1 and SLC35E1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCOLN1	SLC35E1
Description		mucolipin TRP cation channel 1	solute carrier family 35 member E1
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Late Endosome Membrane Cell Projection Intracellular Membrane-bounded Organelle Receptor Complex	Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Cation Channel Activity Iron Ion Transmembrane Transporter Activity Protein Binding Lipid Binding NAADP-sensitive Calcium-release Channel Activity Intracellular Phosphatidylinositol-3,5-bisphosphate-sensitive Cation Channel Activity Ligand-gated Calcium Channel Activity	Protein Binding Antiporter Activity
	Biological Process	Adaptive Immune Response Cation Transport Calcium-mediated Signaling Transferrin Transport Iron Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Cellular Response To PH Phagosome Maturation Autophagosome Maturation	Transmembrane Transport
Pathways		TRP channels Transferrin endocytosis and recycling
Drugs
Diseases		Mucolipidosis IV
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494) Opioid overdose severity score ( 31362332)
Interacting Genes		5 interacting genes: APPBP2 GPR35 SEC22A SLC35E1 TRIM27	6 interacting genes: ABCF3 FTHL17 FXYD6 LAMA3 MCOLN1 MPP1
Entrez ID		57192	79939
HPRD ID		05582	15373
Ensembl ID		ENSG00000090674	ENSG00000127526
Uniprot IDs		Q9GZU1	A0A024R7G7 Q96K37
PDB IDs		5TJA 5TJB 5TJC 5WJ5 5WJ9 6E7P 6E7Y 6E7Z
Enriched GO Terms of Interacting Partners?
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