TNIP3 and KPNA3

Data Source:
BioGRID (two hybrid)

		TNIP3	KPNA3
Description		TNFAIP3 interacting protein 3	karyopherin subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Nuclear Pore Nucleoplasm Cytosol Host Cell
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus
Pathways		Ovarian tumor domain proteases	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23468962) Multiple sclerosis ( 31604244)	Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triiodothyronine/thyroxine ratio ( 30824882)
Interacting Genes		27 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNFAIP3 TNIP1 TRIM55 TRIM63 TRIM8 UBC ZBTB8A	54 interacting genes: ANKRD11 APOL6 ARNT BAHD1 BRD3 CCDC102B CDKN1B COIL CYHR1 DDX21 EPAS1 EPHA2 ERCC3 ESR2 FAM214B FAM50B FAM90A1 FTL GATA6 GRB10 GTF2H1 GTF2IRD1 HEXIM2 HIF1A HNRNPC HSPB1 KAT5 KPNB1 L3MBTL4 MAPK9 MAT2B MVP MYOD1 NFE2L2 NFKB1 NMNAT1 NUP50 POLR3C RAD52 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TNIP3 TSSC4 UVSSA ZBTB24 ZCCHC10 ZCCHC12 ZNF131 ZNF76 ZNF764
Entrez ID		79931	3839
HPRD ID		16268	03536
Ensembl ID		ENSG00000050730	ENSG00000102753
Uniprot IDs		Q96KP6	A0A024RDV7 O00505
PDB IDs
Enriched GO Terms of Interacting Partners?
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