KPNA3 and GTF2IRD1

Data Source:
BioGRID (two hybrid)

		KPNA3	GTF2IRD1
Description		karyopherin subunit alpha 3	GTF2I repeat domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol Host Cell	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triiodothyronine/thyroxine ratio ( 30824882)	Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)
Interacting Genes		54 interacting genes: ANKRD11 APOL6 ARNT BAHD1 BRD3 CCDC102B CDKN1B COIL CYHR1 DDX21 EPAS1 EPHA2 ERCC3 ESR2 FAM214B FAM50B FAM90A1 FTL GATA6 GRB10 GTF2H1 GTF2IRD1 HEXIM2 HIF1A HNRNPC HSPB1 KAT5 KPNB1 L3MBTL4 MAPK9 MAT2B MVP MYOD1 NFE2L2 NFKB1 NMNAT1 NUP50 POLR3C RAD52 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TNIP3 TSSC4 UVSSA ZBTB24 ZCCHC10 ZCCHC12 ZNF131 ZNF76 ZNF764	24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5
Entrez ID		3839	9569
HPRD ID		03536	08379
Ensembl ID		ENSG00000102753	ENSG00000006704
Uniprot IDs		A0A024RDV7 O00505	E9PFE2 Q9UHL9
PDB IDs			2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?
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