KPNA3 and BRD3

Data Source:
BioGRID (two hybrid)

		KPNA3	BRD3
Description		karyopherin subunit alpha 3	bromodomain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol Host Cell	Nucleus
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Chromatin Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus	Chromatin Organization Regulation Of Transcription By RNA Polymerase II
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triiodothyronine/thyroxine ratio ( 30824882)	Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 31798171 29760442) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Estimated glomerular filtration rate ( 31152163) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Intraocular pressure ( 29617998 30591961) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494 27863252) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 22139419 32888494) Platelet distribution width ( 27863252) Red cell distribution width ( 32888494 27863252 28957414) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		54 interacting genes: ANKRD11 APOL6 ARNT BAHD1 BRD3 CCDC102B CDKN1B COIL CYHR1 DDX21 EPAS1 EPHA2 ERCC3 ESR2 FAM214B FAM50B FAM90A1 FTL GATA6 GRB10 GTF2H1 GTF2IRD1 HEXIM2 HIF1A HNRNPC HSPB1 KAT5 KPNB1 L3MBTL4 MAPK9 MAT2B MVP MYOD1 NFE2L2 NFKB1 NMNAT1 NUP50 POLR3C RAD52 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TNIP3 TSSC4 UVSSA ZBTB24 ZCCHC10 ZCCHC12 ZNF131 ZNF76 ZNF764	7 interacting genes: APP BRD7 KPNA3 MAP1LC3B MYC SPOP SPP1
Entrez ID		3839	8019
HPRD ID		03536	03327
Ensembl ID		ENSG00000102753	ENSG00000169925
Uniprot IDs		A0A024RDV7 O00505	A0A024R8H6 B4DS09 Q15059
PDB IDs			2E7N 2NXB 2OO1 2YW5 3S91 3S92 5A7C 5HFR 5HJC 6BGG 6BGH 6I41 6I5P 6I68 6I7A 6QJU 6U4A 6ULP
Enriched GO Terms of Interacting Partners?
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