ZNF669 and BICD2

Data Source:
BioGRID (two hybrid)

		ZNF669	BICD2
Description		zinc finger protein 669	BICD cargo adaptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Cytoskeletal Anchor Activity Small GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Protein Transport Protein Localization To Organelle Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center
Pathways		Generic Transcription Pathway	COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Height ( 31562340) Malaria ( 31844061) Neutrophil count ( 32888494) Platelet count ( 32888494) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count ( 32888494)
Interacting Genes		19 interacting genes: ARMC7 BICD2 CABP5 CCDC136 CDR2L CEP70 CYSRT1 GOLGA6L9 KRT27 KRTAP1-1 KRTAP10-6 KRTAP10-8 MDFI MID2 MTUS2 PNMA2 TRAF1 ZC4H2 ZNF330	42 interacting genes: ARHGAP45 CBR3 CCDC187 CCHCR1 DCTN1 DCTN2 DCX FAM110A FAM161A FAM161B FAM50B GSK3B HDAC4 LNX1 MFAP1 MOS NEK9 PMF1 POLDIP3 PPP1R18 PRPF18 PRPF31 RAB6A RAB6B RBM41 SNW1 TBRG4 TCEA2 TCEANC TSGA10IP USP2 UTP14C YES1 ZC2HC1C ZMAT2 ZNF417 ZNF624 ZNF648 ZNF669 ZNF670 ZSCAN12 ZSCAN23
Entrez ID		79862	23299
HPRD ID		07783	09826
Ensembl ID		ENSG00000188295	ENSG00000185963
Uniprot IDs		Q96BR6	Q8TD16 Q96FU2
PDB IDs			6OFP 6PSE
Enriched GO Terms of Interacting Partners?
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