BICD2 and MOS

Data Source:
BioGRID (two hybrid)

		BICD2	MOS
Description		BICD cargo adaptor 2	MOS proto-oncogene, serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Cytoplasm Cytosol
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Small GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Protein Transport Protein Localization To Organelle Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Signal Transduction Regulation Of Meiotic Nuclear Division Positive Regulation Of MAPK Cascade Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061) Neutrophil count ( 32888494) Platelet count ( 32888494) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count ( 32888494)	Height ( 18391951) Refractive error ( 32231278)
Interacting Genes		42 interacting genes: ARHGAP45 CBR3 CCDC187 CCHCR1 DCTN1 DCTN2 DCX FAM110A FAM161A FAM161B FAM50B GSK3B HDAC4 LNX1 MFAP1 MOS NEK9 PMF1 POLDIP3 PPP1R18 PRPF18 PRPF31 RAB6A RAB6B RBM41 SNW1 TBRG4 TCEA2 TCEANC TSGA10IP USP2 UTP14C YES1 ZC2HC1C ZMAT2 ZNF417 ZNF624 ZNF648 ZNF669 ZNF670 ZSCAN12 ZSCAN23	56 interacting genes: ACTN2 ASB6 ATRIP BICD2 BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 DZIP1 GFAP GOLGA2 GOLGA6A GOLGA6L9 GRAP2 HOMER3 HOMEZ HSPA1A IKZF1 KCTD6 KIFAP3 KIFC3 KRT13 KRT15 KRT27 KRT31 KRT33B KRT34 KRT40 KRTAP1-3 LZTS2 MAP2K2 MEOX2 MID2 MIPOL1 MTMR9 MTUS2 MYOD1 NBPF19 NOTCH2NLA PICK1 PPP2R5A PSTPIP1 RHOU SEC24C SSX2IP TP53BP2 TRAF1 TRAF2 TRIM27 USHBP1 ZBTB2
Entrez ID		23299	4342
HPRD ID		09826	01816
Ensembl ID		ENSG00000185963	ENSG00000172680
Uniprot IDs		Q8TD16 Q96FU2	P00540
PDB IDs		6OFP 6PSE
Enriched GO Terms of Interacting Partners?
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