GEMIN6 and STRAP

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)
HPRD (in vitro)

		GEMIN6	STRAP
Description		gem nuclear organelle associated protein 6	serine/threonine kinase receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex
	Molecular Function	Protein Binding	RNA Binding Signaling Receptor Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Import Into Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal SnRNP Assembly Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathways		snRNP Assembly	Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ACOT11 DDIT4L GEMIN7 NUFIP1 RASL11B RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4	27 interacting genes: CHEK2 GEMIN6 GEMIN7 MAP1B MTRES1 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2
Entrez ID		79833	11171
HPRD ID		06110	05816
Ensembl ID		ENSG00000152147	ENSG00000023734
Uniprot IDs		Q8WXD5	B0AZV0 Q9Y3F4
PDB IDs		1Y96
Enriched GO Terms of Interacting Partners?
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