STRAP and SUMO4

Data Source:
HPRD (in vivo)

		STRAP	SUMO4
Description		serine/threonine kinase receptor associated protein	small ubiquitin like modifier 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex	Nucleus SUMO Ligase Complex
	Molecular Function	RNA Binding Signaling Receptor Binding Protein Binding	Molecular_function Protein Tag Ubiquitin-like Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal SnRNP Assembly Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Localization To Nucleus
Pathways		Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS			Dupuytren's disease ( 28886342)
Interacting Genes		27 interacting genes: CHEK2 GEMIN6 GEMIN7 MAP1B MTRES1 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2	75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		11171	387082
HPRD ID		05816	10584
Ensembl ID		ENSG00000023734	ENSG00000177688
Uniprot IDs		B0AZV0 Q9Y3F4	Q6EEV6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?