SUV39H2 and FAM20C

Data Source:
BioGRID (two hybrid)

		SUV39H2	FAM20C
Description		suppressor of variegation 3-9 homolog 2	FAM20C golgi associated secretory pathway kinase
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor Manganese Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Protein Phosphorylation Biomineral Tissue Development Post-translational Protein Modification Cellular Protein Metabolic Process ATP Metabolic Process Enamel Mineralization Odontoblast Differentiation
Pathways		PKMTs methylate histone lysines	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases			Raine syndrome; Lethal osteosclerotic bone dysplasia
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Allergic rhinitis ( 25085501) Alzheimer's disease in APOE e4- carriers ( 25778476)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	7 interacting genes: FAM118B PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1
Entrez ID		79723	56975
HPRD ID		07580	13298
Ensembl ID		ENSG00000152455	ENSG00000177706
Uniprot IDs		Q9H5I1	Q8IXL6
PDB IDs		2R3A 6P0R	5YH3
Enriched GO Terms of Interacting Partners?
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