SUV39H2 and MYL12A

Data Source:
BioGRID (two hybrid)

		SUV39H2	MYL12A
Description		suppressor of variegation 3-9 homolog 2	myosin light chain 12A
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Cytosol Myosin Complex Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	Calcium Ion Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Muscle Contraction Platelet Aggregation
Pathways		PKMTs methylate histone lysines	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs Ephrin signaling Smooth Muscle Contraction
Drugs			4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Night sleep phenotypes ( 27126917) QRS duration ( 27577874)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	4 interacting genes: CDKN2A HSPB1 PTEN SUV39H2
Entrez ID		79723	10627
HPRD ID		07580	14735
Ensembl ID		ENSG00000152455	ENSG00000101608
Uniprot IDs		Q9H5I1	J3QRS3 O14950 P19105
PDB IDs		2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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